Neurology and Psychiatry

Raha Solution

Raha En 3d

Indications

For the treatment of opiate addiction and cigarette addiction .

Dosage

Take 2 teaspoonful of solution, 3 times a day before meals with a half glass of water.

Contraindication

Contraindication :in sensitive individuals to plant materials if should be used with caution.
Side effects :With very high dosage , nausea , vomiting and diarrhea may be seen .
Pregnancy and Lactation : During pregnancy and Lactation Raha products are not recommended .

Composition

The following hydroalcoholic extracts are found in these products:
1.Berberis vulgaris . 2. Valeriana officinalis . 3. Matricaria chamomilla . 4. Salix alba 5. peganum harmala

Drug Form

120cc oral solution

Active ingredients

Berberis vulgaris :
Isoquinoline , berberine, berbamine , berberrubine , brulacine, columbamine .
Valeriana officinalis : Valepotriate , valtrate , didrovaltrate , acevaltrate , eugenol , valerianol , cratinine , valerine , skytanthine, ,eugenol
Salix alba: Phenolic compounds; salicin , salicortin , teramulacin , fragilin , triandrin , vimalin , vanilic, caffeic and paralogic acids , flavonoids including isoquercetin ,naringin Matricaria chamomilla :Sesquiterpenes( bisabolol chamazulene),Flavonoids(apigenin glycosides ) quercetin , apiin, luteolin
Peganum harmala : Harmine , harmaline , harmalol , Peganine
,vasicine , vasicinone , quinazoline

Reference

1- Gilman A .G . Goodman L S Rall T W ed: The Pharmacological basis
of therapeutics. Macmillan Publishing , New York , N.Y . 2002. 2- Nebelkopf E. : Herbal therapy in the treatment of drug use . Int
J.Addict. 1987 Aug , 22 ( 8) :695 – 717 .
3- Raftari S. and Moattar . F. : Clinical trials on herbal formula for opiate
addiction . Isfahan University of Medical Sciences. Pharm D. Thesis Feb 1990.
4- List P.H : Hagers Handbuch der Parmazeutischen Praxis 1972 , vol 3 . PP 418-20 .
5- Mahmoudian M , Jalilpour H , and Salehian P. : Effect of Peganum harmala I.J.P.T. : 4 . 2002 .
6- Wang YX ,Yao XJ,Tan YH: J. Cardiovasc Pharmacol 1994 ; 23 ( 5) . 7-Hua Z.Wang XL.Yao Hsueh Pao 1994,116(6)2667 – 2672 .
8- Yao ,W.K . et al. : Acta Pharmacol , Sin 7 , 511 , 1986 .
9- Takase H, Yamamoto K , et al. : Nippon Yakurigaku Zasshi 1993 .
102(2) : 101 – 112 .
10- Leathwood PD , et al. : Pharmacol Biochem Behav , 1982 ; 17 : 65
– 71 .
11- Gerhard U , et al. : Schweiz Rundsch Med Prax 1996; 85 ( 15) :
473- 81 .
12- Santos , Ms et al. : Planta Medica , 1994 . 60,278-279.
13- Dehghan . G, et al. : The study of mode of action of Berberis
vulgaris in the reduce of morphine withdrawal syndrome signs in the male mouse . Abst of the 10 th Iranian Congress of Physiology and Pharmacology , Ahwas ( 1991) , P. 280 .